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Parkinson’s Disease: Causes, Symptoms, and Treatment
The degenerative neurological condition Parkinson's disease (PD) influences coordination and movement. It results from brain dopamine-producing neurones degenerating, especially in the substantia nigra. Though its exact origin is unknown, environmental and genetic elements could help it evolve.
Parkinson's disease mostly causes tremor, muscle rigidity, bradykinesia—slowed movement, and postural instability. Patients could also have non-motor symptoms like sadness, sleep problems, cognitive impairment, and loss of smell, which usually get worse over time and hinder everyday activities and general quality of life.
Though there is no cure for Parkinson's disease, treatment focusses on symptom management. Medications including levodopa, dopamine agonists, and MAO-B inhibitors assist in managing dopamine levels in the brain, thereby enhancing movement control. Deep brain stimulation (DBS) surgery can offer considerable alleviation in advanced patients. Furthermore, improving mobility and lowering problems include physical treatment, a balanced diet, and frequent exercise.
Early diagnosis and a multimodal approach enable those with Parkinson's to enjoy fulfilled lives. New treatment approaches, including gene therapy and neuroprotective methods, are under constant investigation, giving hope for improved disease control going forward.